New Roots Herbal Devil's Claw - Devil’s claw has been used in Africa and Germany for ailments relating to the liver and kidneys as well as to the nervous, respiratory, and lymphatic systems. The most popular application of this plant is for the treatment of the swelling and inflammation of the joints that are common symptoms of arthritis, gout, and rheumatism. Studies have shown the active ingredient in Devil’s claw, harpagosides, to be effective in pain relief of the back, neck, and shoulders, as well as some commercial anti-inflammatories, without any side effects, with use over four years.